(CNN) The arrest of
President Donald Trump's former campaign manager
Paul Manafort Monday and former Trump campaign official Rick Gates saddled the White House with a grave new political reality.
By taking one or more people into custody,
a prospect first reported by CNN Friday, Justice Department special counsel Robert Mueller ushers in a perilous time for the White House, reflecting the gravity of the investigation into Russia's interference in the 2016 election and alleged collusion by
Trump's associates.
The special counsel announced that Manafort and Gates have been indicted by a federal grand jury. The 12-count indictment is on "conspiracy against the United States, conspiracy to launder money, unregistered agent of a foreign principal, false and misleading FARA statements, false statements, and seven counts of failure to file reports of foreign bank and financial accounts."

Mueller's decision to examine Manafort's past business relationships with Russia and possible tax arrangements offer a signal how he interprets his understanding of the nature of his mandate, which could have implications for how he proceeds in his investigations into others in Trump's circle.
Just the idea that someone who was once close to Trump has been charged with a federal crime -- even if as yet it's unrelated to the 2016 campaign -- brings political problems of its own.
Trump and his team deny any wrongdoing, and so far there is no conclusive evidence from Mueller's closely held investigation or several congressional probes of nefarious links with the Russians.
At minimum, news of charges will complicate the White House's argument that the Russia drama is nothing but a drummed up Democratic plot born of despair at Hillary Clinton's shocking loss last November, and be a distraction from the Republican tax reform effort this week.
More significantly, the charges could be the first step in a series of actions by the special counsel that strike at the heart of Trump's inner political and family circle, and could even put his presidency in jeopardy.
But the immediate political fallout of whatever unfolds in the coming days depends on who is initially targeted by Mueller, their proximity to Trump, and how the President reacts to this threshold being crossed.
"The Dems are using this terrible (and bad for our country) Witch Hunt for evil politics, but the R's ... are now fighting back like never before," Trump tweeted Sunday. "There is so much GUILT by Democrats/Clinton, and now the facts are pouring out. DO SOMETHING!"
The special counsel has taken up several strands of inquiry, including into the business affairs of Manafort, claims that members of the President's campaign team -- such as former national security adviser Michael Flynn -- transgressed in their alleged contacts with Russian officials and whether the President's dismissal of FBI Director James Comey amounted to obstruction of justice.