This thread is just for academic research and tracking of market behavior. Quoted prices/positions are raw market data to support certain observations quantitatively. They are also used to test rational reasons against future market behaviors.
As to decision on capital allocation, be it speculation or investment, Buffett said one should look into a mirror and work with whom one sees to make the decision.
Fighting against Market is never a good idea. The fact that market goes crazy doesn't necessarily mean it will become sane soon. It can stay crazy longer than one can stay liquid.
For highly speculative event as FDA decision, it is never a good idea to stand in the way even if one is sure it is not a train. There is no 20/20 vision on FDA decision. Therefore, one may choose not to join the craziness, one shouldn't bet against it either.
Reading original works of Buffett a few times over is probably the only sensible way to figure out how to take advantage of the craziness, if one chooses to do at all.