新冠疫苗“混打”效果如何?欧洲三项研究显示:效果加倍!

billwanhua

本站元老
注册
2005-07-07
消息
5,271
荣誉分数
1,584
声望点数
373

在西班牙政府支持开展的研究中,670人先接种了一剂阿斯利康疫苗,八周后其中450人又接种了辉瑞疫苗。研究人员发现,混合接种疫苗的受试者血液中的IgG抗体比仅接种一剂阿斯利康的对照组高出30至40倍。


与此同时,混合接种疫苗的受试者在接种辉瑞疫苗后,体内的中和抗体水平增加七倍,相比之下,接种两剂阿斯利康疫苗的受试者中和抗体水平仅增加两倍。


德国柏林夏里特大学医院展开的研究也同样让受试者先接种阿斯利康疫苗,10至12周后再接种辉瑞疫苗。结果发现,混合接种疫苗的受试者所产生的抗体与接种两剂辉瑞疫苗者不相上下,而更令人鼓舞的是“混打”组的T细胞免疫反应更佳,T细胞可以增强抗体反应以及协助消除已受感染的细胞。


德国萨兰大学的实验也得到类似结果,而且科学家发现第一剂接种阿斯利康疫苗、第二剂接种辉瑞疫苗的受试者,体内抗体是两剂都接种阿斯利康疫苗者的10倍,对活化T细胞的效果也更好。
 

向问天

日月神教光明左使
VIP
注册
2012-09-04
消息
60,382
荣誉分数
10,985
声望点数
1,273
有没有第一针打辉瑞,第二针打阿斯利康的?
 

billwanhua

本站元老
注册
2005-07-07
消息
5,271
荣誉分数
1,584
声望点数
373
有没有第一针打辉瑞,第二针打阿斯利康的?
混打有理论依据,因为第一针产生抗体以后,抗体会对第二针的疫苗起消灭作用。

感觉欧洲不是真正测试混打,而是为了解决以前打了AZ,改打辉瑞是不是有问题,因为他们已经停了AZ。这种实验政治倾向明显,要抱怀疑态度。

如果真正研究混打,就是测试各种组合,英国好像在测试
 

lindamy

时代广场舞照跳
VIP
注册
2005-11-23
消息
25,238
荣誉分数
6,289
声望点数
373
巴西小城在试验半支AZ疫苗。

1 hr 42 min ago

Small town in Brazil to give only half dose of AstraZeneca vaccine as part of trial​

From journalists Rodrigo Pedroso and Tatiana Arias

Residents of Viana, a small town in southeastern Brazil, are taking part in a new coronavirus study in which medical researchers are trying to vaccinate all of the town's adult population ages 18 to 49 against Covid-19, but with only half the typical dose of AstraZeneca's vaccine.

In the study, most of Viana’s adult population will be given two half-doses of the AstraZeneca vaccine three months apart – the usual timespan in which AstraZeneca doses are administered in Brazil. The researchers from Brazil’s Fiocruz Foundation are examining whether a half-dose can provide enough protection against the virus, and then compare its efficacy with the full dosage.

“AstraZeneca studied some individuals and found antibody levels similar to the standard dose in all age groups. Our hypothesis is that half a dose is enough to generate protection against Covid-19. We expect at least 60% of effectiveness,” project head Dr. Valeria Valim, also professor at Espirito Santo Federal University, said during a press conference on June 4.
The study aims to vaccinate 35,000 people, around 85% of Viana's population.

The town was chosen for its closeness to the metropolitan region of Vitoria, Espirito Santo state’s capital, which is a Covid-19 hotspot.

The first round of vaccinations is expected to take two days, to be administered on Sunday, June 13 and Monday, June 14, and will be done using AstraZeneca doses donated by the Brazilian health ministry.
 

billwanhua

本站元老
注册
2005-07-07
消息
5,271
荣誉分数
1,584
声望点数
373
西方又按照高兽医的方法走一遍,混打,打三针,都是第一次从高福口中先说出来的,当时大家笑声一片,被笑话的人往往是先行者
 
最后编辑:
顶部