McGill关于伊维菌素的文章。加拿大卫生部警告不要使用抗寄生虫药伊维菌素治疗 COVID-19 (题目对应最后更新的文章)

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你不是牛马,美国FDA呼吁停止服用牲畜驱虫剂伊维菌素(Ivermectin)作为治疗或预防 COVID-19 的方法。

'You are not a cow': FDA begs Americans to stop taking drug meant for livestock as COVID-19 remedy​

Published Aug. 21, 2021 3:37 p.m. ET

TORONTO -- The U.S. Food and Drug Association (FDA) has issued a plea for Americans to stop taking a drug often used as a de-wormer in livestock as a method to treat or prevent COVID-19.

 
最后编辑:

伊维菌素(Ivermectin)成不了抗新冠病毒主力药物的机理简介​


来源: 科普闲谈 于 2021-08-25 07:46:37
伊维菌素(Ivermectin)成不了抗新冠病毒主力药物的机理简介
科普闲谈

2021年8月25日​
至今为止,作为老药新用的伊维菌素是新冠病毒候选药物中争议最多的一位。从医药界到临床应用,从政界到民间,正反两方势均力敌,没有哪一方有退让或协商的迹象。有独断乾坤的临床试验,在世界各地做了不少,只是结果往往大相庭径,让情况变得更加扑朔迷离。现在的一种趋势是各自为政,专家们的信誉变得苍白无力,医药学面临着前所未有的挑战。

去年年底,作者的邻居送来一条新闻,说有医生在国会的听证会上陈述,伊维菌素在治疗新冠肺炎病人中创造了奇迹。由于当时忙于其他事务,就简单地看了一下伊维菌素在人体内的作用情况,然后告诉邻居此药没那么神奇。

在过去的七个多月中,由于世界各地的科学家和医生们的不懈努力,现在对新冠病毒的各种行为方式和特性有了更透彻的了解。换句话说,对抗病毒药物效能的理解有了一个比较坚实的基础。

仅仅从抗病毒的途径看,伊维菌素是一个很不错的候选药,它是一类抗病毒药物的典型代表。此类药物对付病毒有三个绝招:1. 防病毒复制;2. 防病毒进入宿主细胞;3. 防病毒在宿主细胞内复制后逃出,去感染更多的细胞。有的药物只会前两招,伊维菌素三招都会,但不是很强。随便说一下,FDA很早以前批准的抗其他病毒的药中,有伊维菌素的家族成员。这几个月来,作者与各国的学者和医生们交流了这些成果。

武侠小说里谈到金钟罩铁布衫一类的外家功夫时,都会提到一个致命的弱点,那就是命门。伊维菌素有一个突出的弱点,那就是它在包括肺在内的呼吸系统里没有有意义的靶区,它的主靶区在肝内,其次是肾等器官。靶区是什么意思呢?它就是药物捕杀病毒或它病源的狩猎区。新冠病毒引起的基本上是呼吸系统的疾病,后期会发展到身体的其它部位。由此看来,伊维菌素只能起到一种辅助的作用;它帮人体守护着一些重要的器官,让人体的免疫系统能腾出手来去保护呼吸系统。这样做有没有必要呢?答案是因人而异,伊维菌素无法提供保护呼吸系统那类药物的效用。是不是服用比不服用好呢?个人认为,这是自己对自己负责的一种选择,没有人可以提供答案。

至少有一种伊维菌素的家族成员在治疗新冠病人早期的临床试验中显示疗效,在肺部也有特定的靶区,但它不会前面提到的第三种绝招,而且只对轻症而言。这个结果间接地说明,此类药物的疗效还是有局限性。

目前药物研发工作有不少重大缺陷,其中之一就是研制方向与民众的需求严重脱节。试想一下,规劝大家不要服用牛药马药,那人药在哪呢?

 

美国医学会,药剂师协会等 AMA, APhA,ASHP 关于停止使用伊维菌素(Ivermectin)治疗 COVID-19 的声明​


AMA, APhA, ASHP statement on ending use of ivermectin to treat COVID-19​

SEP 1, 2021​


WASHINGTON, DC – The American Medical Association (AMA), American Pharmacists Association (APhA), and American Society of Health-System Pharmacists (ASHP) strongly oppose the ordering, prescribing, or dispensing of ivermectin to prevent or treat COVID-19 outside of a clinical trial.

Ivermectin is approved by the U.S. Food and Drug Administration (FDA) for human use to treat infections caused by internal and external parasites. It is not approved to prevent or treat COVID-19. Ivermectin is also available to treat certain veterinary conditions; medications formulated or intended for use in animals should not be used by humans. We are alarmed by reports that outpatient prescribing for and dispensing of ivermectin have increased 24-fold since before the pandemic and increased exponentially over the past few months. As such, we are calling for an immediate end to the prescribing, dispensing, and use of ivermectin for the prevention and treatment of COVID-19 outside of a clinical trial. In addition, we are urging physicians, pharmacists, and other prescribers—trusted health care professionals in their communities—to warn patients against the use of ivermectin outside of FDA-approved indications and guidance, whether intended for use in humans or animals, as well as purchasing ivermectin from online stores. Veterinary forms of this medication are highly concentrated for large animals and pose a significant toxicity risk for humans.

The U.S. Centers for Disease Control and Prevention (CDC) and the FDA have issued advisories indicating that ivermectin is not authorized or approved for the prevention or treatment of COVID-19. The National Institutes of Health, World Health Organization, and Merck (the manufacturer of the drug) all state there is insufficient evidence to support the use of ivermectin to treat COVID-19. The Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 also recommend against the use of ivermectin outside of a clinical trial.

Use of ivermectin for the prevention and treatment of COVID-19 has been demonstrated to be harmful to patients. Calls to poison control centers due to ivermectin ingestion have increased five-fold from their pre-pandemic baseline. A recent CDC Health Alert Network Advisory (PDF) recommends that health care professionals should counsel patients against use of ivermectin as a treatment for COVID-19, including emphasizing the potentially toxic effects of this drug, including “nausea, vomiting, and diarrhea. Overdoses are associated with hypotension and neurologic effects such as decreased consciousness, confusion, hallucinations, seizures, coma, and death.”

For more information, we encourage patients and health care providers to consult the FDA’s Consumer Update on Why You Should Not Use Ivermectin to Treat or Prevent COVID-19 and the CDC Health Alert Network Advisory on the Rapid Increase in Ivermectin Prescriptions and Reports of Severe Illness Associated with Products Containing Ivermectin to Prevent or Treat COVID-19.

Patients are encouraged to talk to their physicians, pharmacists, and other prescribers about currently available therapies authorized or approved for the treatment or prevention of COVID-19. The most effective ways to limit the spread of COVID-19 are to get vaccinated, wear a face mask, stay at least six feet from others in public places, wash hands frequently, and avoid large crowds of people. Our organizations strongly urge eligible unvaccinated individuals to get vaccinated.

 
最后编辑:
第一篇太缺德!明明有人用的依维菌素,偏偏强调是畜生用的。
 
Use of ivermectin for the prevention and treatment of COVID-19 has been demonstrated to be harmful to patients. Calls to poison control centers due to ivermectin ingestion have increased five-fold from their pre-pandemic baseline. A recent CDC Health Alert Network Advisory (PDF) recommends that health care professionals should counsel patients against use of ivermectin as a treatment for COVID-19, including emphasizing the potentially toxic effects of this drug, including “nausea, vomiting, and diarrhea. Overdoses are associated with hypotension and neurologic effects such as decreased consciousness, confusion, hallucinations, seizures, coma, and death.”
 
说了一堆,结果,原因落在overdoes上。

他们有一丝一毫的智商吗?
 

民众痴迷服驱虫药偏方抗新冠 美国这一州救护车忙翻​

文章来源: 苹果日报 于 2021-09-04 14:02:50 - 新闻取自各大新闻媒体,新闻内容并不代表本网立场!



美国部分民众不打疫苗却听信偏方,擅自服用驱虫药“伊维菌素”(ivermectin)来预防或治疗新冠肺炎,反而引发身体不适、需要送医治疗,消耗医疗能量。奥克拉荷马州一名在乡村的医生表示,当地医院和救护车忙着照顾这些使用驱虫药的患者,导致其他需要救治的病患延误治疗。

奥克拉荷马州医生麦伊莱(Jason McElyea)对当地电视台表示,他在该州的东部和东南部医院都有看诊,这两区的医院最近患者满溢,因为当地居民相信伊维菌素可以对抗新冠肺炎,所有服用了整整一匹马平时抗寄生虫所需要的剂量,结果需要叫救护车。

民众因此大量涌入急诊室和住院病房,医院在人力和床位不足的情况下暂停接收新患者,救护车也就无法载人来,甚至根本就无法出动。服用驱虫药的民众占用了医疗资源,麦伊莱说,他的同事不得不将一名新冠重症患者送到隔壁州的医院,在这种情况下,如果有枪伤、车祸等突发事件的伤者,也无法即刻救治。

麦伊莱说,当地人之所以比较相信伊维菌素、而非疫苗,是因为这些农村居民经常使用这种药物,“在农村小镇长大,我们可能都无意间碰过伊维菌素,这是人们熟悉的东西,也就不那么害怕”,结果有些当地人就自己去买伊维菌素、自己配剂量,无视药品上的警告标语。



不仅奥克拉荷马州,路易斯安那州和华盛顿州也都因为民众服用伊维菌素,导致毒物控制中心工作量增加而发出警告。美国疾病防治中心(CDC)日前宣布一起案例,是民众喝下一头牛所需要的伊维菌素剂量,结果出现幻觉、颤抖,必须住院9天。由于伊维菌素经常用在马身上,推特上许多伊维菌素的迷因图都用马或人马来作为讽刺。

目前没有任何研究证实伊维菌素能对抗新冠肺炎。美国食品药物管理局(FDA)警告,服用大量伊维菌素相当危险,可能导致恶心、恶心、呕吐、腹泻、癫痫、神智不清、甚至死亡。

属于保守州份的奥克拉荷马州,是目前美国新冠疫情热区之一,过去一周新增逾1万8400列确诊、189例病殁,疫情爆发至今累计逾8000例死亡病例。

 
所有疫苗,都带入SPIKEprotein进入人体。

SPIKEprotein已经证实是有毒的,不需要病毒其他部分,单单SPIKE蛋白,就杀死了很多人。而且长期作用未知。
是的,我也看到有关文章指明S蛋白是对人体有危害的,而且现有的mRNA疫苗为了其稳定性都是基因改造过的,其中的蛋白质能否会被人体正常消化还是在体内会堆积造成比如痴呆,渐冻症等疾病还未知,而且每个个体的免疫机能不同,除了宣传疫苗的有效性,专家们也应该指出其中的长期,短期风险,这才是应有的科学态度。
 
民众批评抱怨政府疫情控制上不负责,药品开发不积极,测试追踪上偷工减料,政客就跟你玩儿甩锅,看看现在的各级政府,那个不是甩锅给民众接种疫苗,那个政客的Twitter上不是作秀,趁机拼命地嘴把式 “Please get vaccinated”,震天动地,一个比一个喊的响。

搞个什么报道“服用了整整一匹马平时抗寄生虫所需要的剂量,结果需要叫救护车”,以偏概全。有人都给逼的服用马的抗寄生虫的药了,不反省自己来说句同情的话,还嘲笑式的在那儿报道。还糖塞什么”没有数据证明“等等。这甩锅的都流氓式了。
 

今天CNBC文章题为:中国流亡者郭文贵利用网络媒体推销虚假信息及未经证实的治疗Covid - 19 药物.

“记住,青蒿素、伊维菌素、地塞米松、土霉素、羟氯喹和锌是抗击中共病毒的必要药物。根据附属的 GNews 网站上的广播的官方翻译,这几种药物将根除病毒,”郭在周日的 GTV 节目中说。 “此外,青蒿素对接种过一针疫苗的人有效,但对第二针或第三针无效,”他补充说。


郭在他的网站上宣传虚假信息,宣扬关于疫苗的阴谋论,推销各种FAD,CDC没有批准的Covid-19治疗方法,宣称伊维菌素百分之百有效,用过的都治愈了。

郭文贵说给儿童接种疫苗等同谋杀。将会面临无法预测的严重后果。

极力宣传这些虚假信息和未授权的Covid治疗方案和药物的大多是保守派或极右翼的组织和媒体,包括著名保守派主持人Joe Rogan, Dennis Prager, 以及Foxnews等。

Chinese exile Guo Wengui uses misinformation network to push unproven drugs to treat Covid​

PUBLISHED TUE, SEP 7 20212:19 PM EDTUPDATED 30 MIN AGO

Brian Schwartz@SCHWARTZBCNBC

SHAREShare Article via FacebookShare Article via TwitterShare Article via LinkedInShare Article via Email
KEY POINTS
  • Wealthy Chinese exile Guo Wengui is using his online misinformation network to promote the use of unproven treatments for Covid.
  • Guo as recently as last week pushed the drugs ivermectin and artemisinin as Covid treatments.
  • He has also pushed conspiracy theories about vaccines developed by Pfizer and Moderna.
In this article
Fugitive Chinese billionaire Guo Wengui hold a news conference on November 20, 2018 in New York.

Chinese billionaire Guo Wengui hold a news conference on November 20, 2018 in New York.
Don Emmert | AFP | Getty Images

Guo Wengui, a wealthy businessman who fled China in 2014 and is linked to several high-profile far-right personalities in America, has been using his online network to promote unproven drugs to treat Covid-19 while spreading misinformation about the vaccines used to combat the disease.

As recently as Sunday on a livestream, Guo used his show on the online platform GTV to push ivermectin, which is used to treat parasitic infections, and malaria drug artemisinin as ways to battle the coronavirus.

Neither the Food and Drug Administration nor the World Health Organization have approved either drug for treating Covid. The FDA and the Centers for Disease Control and Prevention have warned against using ivermectin to treat and prevent Covid infections.

Guo on Thursday equated vaccinating children with murder. “Please do not take your children to get vaccinated anymore. It is not about getting a shot that simple but equivalent to murder,” he said in a translated video post on social media platform Gettr. “Those who were vaccinated might face an unpredicted severe consequence.”

New study looks at whether Ivermectin actually works for Covid

The CDC recommends that people ages 12 and up get a Covid vaccine, which has been shown to be highly effective in cutting the chances of hospitalization and reducing the spread of the disease. Authorities are expected to approve the use of the vaccine for younger children later this year.

GTV, which routinely features Guo himself, has been described by researchers at Graphika as part of the businessman’s larger media empire and misinformation network.

Guo is among a group of mainly conservative voices who are pushing ivermectin and other unauthorized Covid treatments as President Joe Biden’s administration and state governments struggle to persuade more Americans to get vaccinated. Sixty-two percent of people 12 and up are fully vaccinated in the U.S., according to CDC data.

NBC News reported that a pro-Trump telemedicine website and right-leaning organizations have been some of the biggest purveyors of false information regarding unproven coronavirus treatments.

Guo has been close to former Trump White House chief strategist Steve Bannon for years. A foundation linked to Guo recently hosted an event that featured remarks by Bannon and others tied to former President Donald Trump, including lawyer and former New York Mayor Rudy Giuliani, former national security advisor Michael Flynn and MyPillow CEO and conspiracy theorist Mike Lindell.

Guo fled China in 2014 in anticipation of corruption charges. After Guo criticized China’s leaders, warrants were reportedly issued for his arrest on charges that included corruption and bribery. Guo has denied the charges. He has since been sued by investors in GTV. His attorneys have called the plaintiffs’ accusations “unfounded.”

“Remember, artemisinin, ivermectin, dexamethasone, oxytetracycline, hydroxychloroquine, and zinc are the necessary medicines to fight the CCP [Chinese Communist Party] virus. These few medicines will eradicate the virus,” Guo said during his Sunday episode on GTV, according to an official translation of the broadcast found on the affiliated GNews website. “Also, artemisinin is effective for those who have had one shot of the vaccine, but not the second or third shot,” he added.

That GTV stream has racked up over 7 million views. GTV did not respond to a request for comment after CNBC sent the company a note through its feedback portal.

Steve Bannon pleads not guilty to defrauding border wall donors

Despite warnings from health officials, people who oppose Covid vaccines have turned to ivermectin, which is often used as a deworming medication for horses, although it can also be used to treat parasitic infections in humans.

The hugely popular podcast host Joe Rogan, who has been accused by federal health officials of pushing vaccine misinformation, announced last week he came down with the virus and had been using ivermectin, among other items, to treat his sickness.

“The FDA has not authorized or approved ivermectin for the treatment or prevention of COVID-19 in people or animals. Ivermectin has not been shown to be safe or effective for these indications,” the FDA recently said in a statement. “There’s a lot of misinformation around, and you may have heard that it’s okay to take large doses of ivermectin. It is not okay.”

Beyond Guo and Rogan, others have pushed ivermectin to Covid patients. Conservative radio host Dennis Prager said on his podcast in late July that he used ivermectin as a prophylaxis and, after the FDA came out against the use of ivermectin to treat Covid, accused the agency of “killing tens of thousands of Americans with that statement.”

“I put it to you pretty starkly. Either the FDA is misleading you, or I’m misleading you,” Prager told his audience.

The progressive media watchdog Media Matters said other conservative personalities on Fox News have hyped the use of ivermectin.
Guo has also focused on artemisinin in his recent episodes.

A translation of Guo’s live broadcast from Aug. 30 has a headline that says, “Artemisinin is the antidote for CCP virus, said Mr. Miles Guo.” Miles Guo is one of Guo’s aliases, as is Miles Kwok. The translation on the GNews website shows a picture of an artemisinin capsule container with text saying, “Covid-19 Here Comes the Cure — Artemisinin.”

“Mr. Miles Guo affirmed that Artemisinin, discovered and extracted by Nobel laureate Tu Youyou, is more than 99% effective in curing the CCP virus,” the translation says. “He also reiterated again that all chaptors must stock up on the Ivermectin, Azithromycin, and Oxytetracycline.” The Aug. 30 livestream had 6 million views.

The WHO has said artemisinin, which is an antimalaria drug derived from the artemisia plant, will be tested on hospitalized Covid patients. The WHO said there has yet to be proof of artemisia-derived products being effective in treating Covid-19, the BBC reported.

Guo’s campaign to push ivermectin and artemisinin amounts to the latest example of his misinformation tactics, according to new research from Graphika.
“In promoting artemisinin, Guo and his media network are relying on tactics Graphika and the Virality Project have observed in the amplification of other unproven Covid-19 treatments,” the researchers say in a blog post. “These include ivermectin and hydroxychloroquine, both of which are being promoted by Guo’s network alongside artemisinin.”

Translations of Guo’s posts on Gettr, which is run by Trump advisor Jason Miller, show that the Chinese businessman has also used that medium to push similar concepts about unproven Covid treatments. Miller has said Gettr is funded in part by a foundation tied to Guo.

In a Gettr video post on Saturday, Guo repeatedly touts artemisinin and ivermectin as a Covid treatment.

“Artemisinin is the best, and it definitely works for those who have been vaccinated with the first shot,” a translation of his post said. “Ivermectin is almost 100% effective so far. All patients who have used it are healed,” Guo later adds in the post.

He made similar claims in his video post Thursday on Gettr.

As for the likelihood of getting Covid after receiving a vaccine, data reported by The New York Times gives the odds at about 1 in 5,000 per day. That’s based on information from Utah, Virginia and a county in Washington state. For regions with higher vaccination rates, such as the Chicago, Los Angeles and San Francisco areas, the Times data puts the odds at 1 in 10,000.

 
最后编辑:
看来郭文贵在CFC上已经有不少粉丝,一直宣扬这些东西。。。。
 
喜国麻雀虽小五脏俱全,不能坐吃山空,终归需要钱来供养小麻雀,不容易。。。
 
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