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Data Doesn’t Support New COVID-19 Booster Shots for Most, Says Expert
It’s time to rethink the blanket recommendation for giving the new Omicron booster to everyone
time.com
In a perspective published Jan. 11 in the New England Journal of Medicine, vaccine expert Dr. Paul Offit says it’s time to rethink booster recommendations.
In the third year of the pandemic, the population’s immune situation is vastly different from what it was in 2019 when SARS-CoV-2 emerged. Now, most people have been vaccinated against the virus, been infected with it (once or multiple times), or both. And the latest data show that the newest booster shot, which targets the Omicron BA.4/5 strain and original virus variants in a bivalent formulation, isn’t that much more effective in generating virus-fighting antibodies than the original vaccine when used as a booster.
But COVID-19, and the population’s ability to combat it, has changed since then. For one, the variant of the virus now infecting people—XBB.1.5—is different from the original. Through a combination of the fact that many people now have higher levels of protection from vaccines or having recovered from infections, and the fact that the Omicron variants as a group, BA.4/5 and XBB.1.5 included, do not seem to cause serious disease in most healthy people, the job of booster doses has also evolved. Now, boosting everyone with an Omicron shot is “trying to prevent, in otherwise healthy people, mild illness for a few months,” says Offit, until the next variant comes along to replace it. “That doesn’t make sense.”
“试图防止健康的人得小病几个月”
最后一句就是蔡桓公说的: 医之好治不病以为功
那些强烈呼吁土鳖引进mRNA疫苗的出来辩护一下
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