[问题] a medical question

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A 59-year-old woman with a 60 pack-year smoking history was diagnosed with lung cancer 2 months ago. She now enters the hospital in coma. Her serum calcium is 16 mg/dL. Which of the following would be the most useful to reduce calcium in this patient rapidly ?

A Spironolactone

B Hydrochorothiazide

C Furosemide

D Mannitol

E Acetazolamide

which one is correct and why?

thanks a lot.