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有总比没有强，这个绝对正确！特别是对重症。老向前期把中国疫苗夸得太过了，现在有点跌落神坛的感觉......
智利政府发声：科兴疫苗让重症率下降83.7%，死亡率下降100%，广泛采用科兴疫苗是完全正确的决策
- 主题发起人 向问天
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疫苗并不能完全防治感染，2月以色列的一项60万人的数据显示，打了两针后，607人确诊感染，占0.1%，这些人还是因为出现症状，或者有密切接触阳性病人才做检查的。
有个视频说，各疫苗做试验时的当地发病率不同，感染率就不会一样。
贵圈
政府都对党
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多打。那东西需要很多很多。
billwanhua
本站元老
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Brazil sees 1,803 COVID-19 deaths; Chinese vaccine found 50.7% effective against variant
Brazil on Sunday recorded 1,803 new COVID-19 deaths, as a large study found that a Chinese vaccine that has become the linchpin in the country's vaccination campaign is 50.7% effective against the infectious new homegrown variant known as P1.
Sinovac jab 50.7% effective against Brazil's homegrown variant
The Chinese shot is currently the most widely administered vaccine in the country.
www.freemalaysiatoday.com
The study, which it said had been sent to the medical journal The Lancet for publication, tested 12,400 volunteers across Brazil.
数据姗姗来迟，但是终于有了
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还没有仔细读，问一下，这50%指的是感染，重症，还是死亡？Brazil sees 1,803 COVID-19 deaths; Chinese vaccine found 50.7% effective against variant
Brazil on Sunday recorded 1,803 new COVID-19 deaths, as a large study found that a Chinese vaccine that has become the linchpin in the country's vaccination campaign is 50.7% effective against the infectious new homegrown variant known as P1.www.reuters.com
Sinovac jab 50.7% effective against Brazil's homegrown variant
The Chinese shot is currently the most widely administered vaccine in the country.
The study, which it said had been sent to the medical journal The Lancet for publication, tested 12,400 volunteers across Brazil.
数据姗姗来迟，但是终于有了
如果我没有理解错，和不打疫苗的对照组比较，高出50%的保护效果，这个指标应当是刚刚符合WHO的标准。起码不会像有些人得出结论：越打越多。
billwanhua
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Butantan said that if the second dose is delayed by more than two weeks, the efficacy rises to 62.3%. The vaccine has an efficacy of between 83.7% and 100% at preventing those infected from requiring medical assistance, it said.
自媒体就算了，还是看大媒，这个应该是最终数据，拿到柳叶刀去发表。
这上面说改变间隔，有效性62.3%
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billwanhua
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综合各大主流媒体报道，我对目前疫苗的有效性有以下总结，纯粹个人观点，非喜勿喷，欢迎讨论：
- 在预防感染有效性方面，mRNA疫苗甩其他各种疫苗几条街。 如果没有变异，疫苗充足，mRNA疫苗应该是最优选择。
- 目前没有确凿数据说明mRNA疫苗比其他各种疫苗对预防ICU或者预防死亡更有效。美国有报道，打了二针mRNA疫苗感染死亡的。其他很多疫苗三期实验都说100%防止死亡，但是实际情况不好说，肯定没有100%
- mRNA疫苗对于变异可能效果不大。打个简单比喻，mRNA疫苗针对特定突刺片段，就像治疗癌症的定向靶药，能够有的放矢，效果当然好，但是如果靶子变了，特别是其他片段，效果可想而知。目前多个研究都证明mRNA对南非变种效果不大。以色列实战降低8倍（https://www.forbes.com/sites/williamhaseltine/2021/04/11/the-pfizerbiontech-covid-19-vaccine-is-less-effective-against-the-south-african-and-uk-variants-than-against-the-original-virus-according-to-a-new-real-world-study-from-israel/?sh=2f14b8bd5888）牛津大学文章说7.6倍（https://www.ox.ac.uk/news/2021-03-18-existing-vaccines-may-protect-against-brazilian-coronavirus-variant）， Moderna自己的研究降低6倍（https://www.aljazeera.com/news/2021/4/11/what-we-know-about-the-south-african-coronavirus-variant）。 可笑的是辉瑞自己根据很少的cases研究得出的结论是对南非病毒100%有效(Trial: Pfizer COVID Vax Effective Against South African Variant).
- 目前不清楚灭活疫苗对于变种的有效性。巴西最近报道好像对P.1比较好（一针接近50%）
- 基本上，以后可能每年都需要打疫苗，目前当务之急是把各种疫苗成本降低到感冒疫苗的水平，要不然大部分国家都会破产。