2 Californians died of coronavirus weeks before previously known 1st US death

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2 Californians died of coronavirus weeks before previously known 1st US death
By Jason Hanna and Sarah Moon, CNN

Updated 1337 GMT (2137 HKT) April 22, 2020



(CNN)New autopsy results show two Californians died of coronavirus in early and mid-February -- up to three weeks before the previously known first US death from the virus.
Doctors try to untangle why they're seeing 'unprecedented' blood clotting among Covid-19 patients

Doctors try to untangle why they're seeing 'unprecedented' blood clotting among Covid-19 patients


These deaths now stand as the country's earliest two attributed to the novel coronavirus, a development that may change the understanding of how early the virus was spreading in the country, health experts told CNN Wednesday.

Two deaths in Northern California's Santa Clara County happened February 6 and 17, the county said Tuesday in a news release.

The previously understood first coronavirus death happened on February 29 in Kirkland, Washington.

Time line
December 31, 2019: China reports mysterious pneumonia cases to the World Health Organization.
January 7, 2020: China says the cases were caused by a new coronavirus.
January 17: US starts screening for symptoms at certain airports.
January 21: First US case confirmed in Washington state.
January 31: US says it will deny entry to foreign nationals who've traveled in China in the last 14 days.
February 6: A person in California's Santa Clara County dies of coronavirus; link not confirmed until April 21.
February 17: A second person in California's Santa Clara County dies of coronavirus; link not confirmed until April 21.
February 26: CDC announces what's then thought to be the first possible US case of community spread, in California.
February 29: A patient dies of coronavirus in Washington state -- then believed to be the country's first novel coronavirus death.


The two in California had no known travel histories to China or anywhere else that would have exposed them to the virus, Dr. Sara Cody, the county's chief medical officer, told The New York Times. They are presumed to have caught the virus through community spread, she told the Times.

"That is a very significant finding," Dr. Ashish K. Jha, director of the Harvard Global Health Institute, told CNN's "New Day" on Wednesday.

"Somebody who died on February 6, they probably contracted that virus early to mid-January. It takes at least two to three weeks from the time you contract the virus and you die from it."

If they did not contract coronavirus through travel abroad, that also is significant, Jha said.

"That means there was community spread happening in California as early as mid-January, if not earlier than that," Jha said.

"We really need to now go back, look at a lot more cases from January -- even December -- and try to sort out when did we first really encounter this virus in the United States," Jha said.

CDC confirmed Tuesday that tissue samples were positive
The Santa Clara County Medical Examiner-Coroner performed autopsies on two people who died in their homes February 6 and 17 and sent samples to the US Centers for Disease Control and Prevention, the county said Tuesday.

The CDC confirmed Tuesday that the tissue samples tested positive for coronavirus, the county said.

A third death in early March was also confirmed to be virus-related, the release said.

At the time of the deaths, the county said, testing for the virus was very limited -- generally restricted only to people with a known travel history and seeking treatment for certain symptoms, and available only through the CDC.

Further details on the victims were not provided.

The county said that as more deaths in the county are investigated, it's likely there will be more that are tied to the virus.

Dr. Colleen Kraft, associate chief medical officer of Atlanta's Emory University Hospital, agreed with Jha about the announcement's significance.

"That also means that a lot more people have had this, probably asymptomatically or with mild illness, than we thought before," Kraft said Tuesday.

CNN's Christina Maxouris contributed to this report.
 
Autopsies reveal first confirmed U.S. coronavirus deaths occurred in California in February

Two coronavirus-infected people died in Santa Clara County on Feb. 6 and Feb. 17, the medical examiner revealed Tuesday, making them first documented COVID-19 fatalities in the United States.

Until now, the first fatality was believed to have occurred in Kirkland, Wash., on Feb. 29.

Officials previously had said the first Silicon Valley death was March 9. But the Santa Clara County medical examiner revealed Tuesday that people who died Feb. 6, Feb. 17 and March 6 also died of COVID-19.

"These three individuals died at home during a time when very limited testing was available only through the [U.S. Centers for Disease Control and Prevention]. Testing criteria set by the CDC at the time restricted testing to only individuals with a known travel history and who sought medical care for specific symptoms," the county said in a statement. "As the Medical Examiner-Coroner continues to carefully investigate deaths throughout the county, we anticipate additional deaths from COVID-19 will be identified."

Silicon Valley was an early center of the coronavirus outbreak. So far it has reported nearly 2,000 cases and eight deaths.

There have been growing concerns that the new coronavirus has been in California longer than experts first believed.

Dr. Jeff Smith, a physician who is the chief executive of Santa Clara County government, said earlier this month that data collected by the CDC, local health departments and others suggest it was “a lot longer than we first believed” — most likely since “back in December.”

“This wasn’t recognized because we were having a severe flu season,” Smith said in an interview. “Symptoms are very much like the flu. If you got a mild case of COVID, you didn’t really notice. You didn’t even go to the doctor. The doctor maybe didn’t even do it because they presumed it was the flu.”

In January and most of February, there was little if any community testing in California.

A preliminary study, conducted by researchers at Stanford University, estimates that between 2.5% and 4.2% of Santa Clara County residents had antibodies to the new coronavirus in their blood by early April. Antibodies are an indication that a person’s immune system has responded to a past infection.

Though the county had reported roughly 1,000 cases in early April, the Stanford researchers estimate the actual number was between 48,000 and 81,000, or 50 to 85 times greater.
 
美国加州2000人的小城对所有愿意参加的人提供免费抗体测试。几天以后将在另外地区试点。

6 hr 21 min ago
This California town is testing every resident for coronavirus and antibodies
From CNN's Augie Martin


A medical professional administers a coronavirus test at a drive thru testing location in Bolinas, California, on April 20.

A medical professional administers a coronavirus test at a drive thru testing location in Bolinas, California, on April 20. Ezra Shaw/Getty Images

A remote Northern California hamlet became one of the first places in the world Monday to attempt to comprehensively test all of its residents for Covid-19 and the antibodies believed to make one immune from infection.

The community-wide free testing effort in Bolinas, California, is voluntary. The town is one of two communities taking part in the new study launched by the University of California, San Francisco with the aim of gaining a more complete understanding of how the virus invisibly spread during the initial shortfall of comprehensive nationwide testing.

Bolinas, with a population of fewer than 2,000 people, sits idyllically on the Pacific Ocean in rural Marin County, just north of San Francisco. Starting this past Monday, residents of this picturesque town have four days to visit a pop-up testing site to receive nasal swabs for Covid-19 infection, as well as submit for a finger prick to test for antibodies.

Five days later, beginning on April 25, and in an entirely different location, nearly 6,000 residents of a section of the densely inhabited Mission District in San Francisco will have four days of their own in which to take advantage of the testing.

Read more here.
 
武汉11月就有案例了,美国人2月死于这个病毒,一点不令人惊讶,11月到封城前,大量武汉人或者到过武汉的人的世界范围的流动,如果世界范围没有开始发生,反而会令人觉得不可思议。春季前后多少武汉人中国人出国旅游?那个时候好像有个数据,非常大
 
现阶段还不到找原因的时候,各方都不要畏惧真相,努力找事实,下一步才是找源头。
 
如果源头是指什么动物载体,按中国讲法目前还没找到
爆发地是武汉应该没有疑问,简单事实而已
 
现阶段还不到找原因的时候,各方都不要畏惧真相,努力找事实,下一步才是找源头。

中国也应该有勇气做类似的研究,查明真相对中国也有好处。
 
最起码要证明不是人造病毒,打脸摸黑的人。
 
12 min ago
First Indiana Covid-19 infections occurred at least 2 weeks before first reported case, authorities say

The US state of Indiana is working to go back and identify every death they think may have been associated with Covid-19 in order to get a more accurate count, according to Indiana Health Commissioner, Dr. Kristina Box.

Dr. Box said the state has tracked cases that go back to at least mid-February, weeks before Indiana’s first reported case in early March.
"There are other individuals that were in the hospital, that may have been discharged with the diagnosis of Covid-19. And that's what we're in the process of trying to make sure that we know all of those individuals, in addition to those deaths," Dr. Box said.
"Because if we only report on the other suspected Covid-19, or presumed Covid-19 deaths, as other states are, but we don't have that underlying number of other people that were sick but didn't die from it, it's going to really inflate that the death rate number for the states.”
Dr. Box said while Indiana should expect to see an increase in deaths posted on Friday as a result of these efforts, the increase will add fewer than a hundred fatalities to the state total.

Indiana today is reporting 394 new Covid-19 infections, and 31 new fatalities, bringing the state’s totals to 12,438 cases and 661 Covid-19 related deaths.
 
9 min ago
A healthy California woman who "suddenly died" becomes first known US coronavirus death

A seemingly healthy 57-year-old woman from California's San Francisco Bay Area "suddenly died" in early February, becoming the first known United States death related to the coronavirus, the Los Angeles Times first reported on Wednesday.

Patricia Dowd, who worked as a manager for a semiconductor company, “exercised routinely, watched her diet and took no medication,” the Times reported.
Dowd’s older brother Rick Cabello confirmed to CNN that she didn’t smoke and that she was in good health.

"She was an athlete in her high school days, she was always active," Cabello said.

Before Dowd was found dead on February 6, "she had flu-like symptoms for a few days, then appeared to recover," the Times reported.

Five days before she died, she called Cabello to tell him she couldn’t make it to a family visit in Stockton, California.

"She wasn’t feeling well, which was very unusual for her," Cabello said. "I remember her specifically saying 'I'm not feeling well,'" he added.

The Los Angeles Times reported that she had cancelled plans to go a weekend funeral.

Dowd started working from home as her condition improved and had been in touch with a colleague around 8 a.m. on the day of her death. She was found dead about two hours later, according to the Times.

Her sudden death was a shock to family members. They all believed it was a heart attack, Cabello said.

New details: On Tuesday, Santa Clara County announced that tissue samples for two people who died in February came back positive for the coronavirus. Both individuals died in their residences in Santa Clara County -- one was a 57-year-old woman who died on February 6 and the other was a 69-year-old man who died on February 17.

The county did not identify or provide any more details of the deaths other than the gender and ages.

In a news conference on Wednesday morning, Santa Clara County Department of Public Health director Dr. Sara Cody said neither case had a recent travel history that would have exposed them to the virus and that they presume each case represents community transmission.

Cabello said Dowd was a frequent world traveler.

A family member told the Times that she had planned to travel to China later this year and went abroad "multiple times a year to different global locations." The Times also reported that Dowd had a history of foreign travel, as did her co-workers at Lam Research.

Dowd was “hardworking, loyal, and caring,” Cabello told the Times.

She was the energy person in her large network of friends,” said Cabello. “She was everybody’s rock.”

In a tribute wall set up for Dowd by the Cusimano Family Colonial Mortuary, a coworker wrote, "I'll always remember the kindness and generosity of her spirit. She was genuinely caring and had an amazing energy."
 
加州补报死亡病例改写美国疫情时间线 美媒怎么看?

文章来源: 纽约时报 于 2020-04-23 08:37:35 - 新闻取自各大新闻媒体,新闻内容并不代表本网立场!

旧金山——在有证据表明新冠病毒在美国存在社区传播几周前,一名57岁的女性出现了类似流感的症状,后来她在位于圣何塞家中的厨房里突然死去,有关部门对其死因展开了调查。她的流感检测结果是阴性。验尸官百思不得其解。她看上去像是出现了一次严重的心脏病发作。

但现在,这名2月6日去世的女子的组织样本显示,她感染了新冠病毒——这一令人震惊的发现改写了该病毒在美国早期传播的时间线,表明在疫情暴发的最初几周里决定了联邦政策的乐观假设是不准确的。

这一出乎意料的新发现清楚地表明,这种病毒最早在1月,在联邦政府于2月2日开始限制来自中国的旅行之前,已在加州湾区传播。这也引发了还有哪些地方有疫情却未被发现的疑问。

在2月,由于疾控中心的检测试剂盒质量不佳,加之检测标准定得太高等原因,当地几乎没有开展检测,所以加州索拉诺县的官员并没有意识到病毒已经到了美国。

此前的感染者都有在疫情暴发地中国的旅行史,或者与患者有过接触。但2月26日索拉诺县的病例的感染源不明。在附近的圣克拉拉县(包括圣何塞)以及华盛顿州和俄勒冈州,很快也发现了类似的社区传播病例。

周二晚些时候公布的新检测结果显示,即使是这条时间线也没能揭示出这种病毒已经传播了多长时间。当局表示,圣何塞的这名女性最近没有出国旅行,但她的死亡却比最早记录到的社区传播病例早了整整20天。2月17日,在圣克拉拉县的另一例此前被认为无关的死亡,现在也确定跟新冠病毒有关。

圣克拉拉县的卫生主管萨拉·科迪(Sara Cody)博士在接受采访时说:“这些死亡,每一例可能都只是冰山的一角。”

加州州长加文·纽瑟姆(Gavin Newsom)周三表示,随着在全州范围内进一步就该病毒的最早起源展开调查,可能还会有“进一步的消息宣布”。他说,调查人员正在查看一些县去年12月的验尸官和尸检报告。

据朋友和家人说,本周发现的这名最早的女性病患在硅谷一家半导体制造公司工作,公司在世界各地设有办事处,包括在最早暴发疫情的中国武汉。

她的一位老朋友说,她在2月2日抱怨自己出现了类似流感的症状。他说,四天后,她还在家里工作,身体仍然感到不适。据这位友人表示,她女儿回家后发现她倒在了厨房的早餐吧台前。为了保护感染者的身份,这位友人要求匿名。

她的家人说,他们一开始就怀疑她是否感染了冠状病毒引起的COVID-19。他们说,她在公司担任审计师,因此会接触到来自世界各地的员工,并且经常出差。

全国范围内,在官方确诊的冠状病毒病例之前,医生和公共卫生官员就已报告了重症和死亡病例。其中一些病例直到现在才得到检测,而圣克拉拉县的新发现表明,这些可疑的早期病例是社区传播的实例,显示出公共卫生应对措施在不断扩大的疫情面前是不足的。

专家们说,如果有更早的证据表明这种病毒已经登陆美国,公共卫生官员就会更迫切地加强检测,为医院做好准备,并且调配防护装备,防止医护人员和其他人感染。

然而2月的工作重点是对数千名从中国归来的旅客进行隔离,希望能够发现、隔离和控制感染。

“如果已经在这里了,那么这样做又有什么意义呢?”传染病专家、约翰·霍普金斯健康安全中心(Johns Hopkins Center for Health Security)高级学者阿迈什·阿达尔贾(Amesh Adalja)博士说。

目前还不清楚最早的死亡者是如何感染这种病毒的。今年1月,卫生官员确认了一系列来自中国的病毒检测呈阳性者,但这些病例基本得到了控制。当时,唐纳德·特朗普总统表示,他不认为这种病毒会成为大流行病,并宣布公共卫生当局“完全控制住了它”。

联邦卫生官员最初主要将检测范围限制在来自武汉的人身上,然后将检测范围扩大到来自中国大陆的人。特朗普下达了旅行限制令,包括自2月2日开始,对从中国大陆返回的美国居民进行健康检查。

到2月26日,特朗普声称,美国有限的病例数量“在几天内将减少到接近于零。我们的工作做得相当棒”。

就在同一天,社区传播开始出现,首先在加州,然后是波特兰、俄勒冈地区,以及西雅图附近。

3月16日,科迪率先发布了美国首个居家令。但她说,如果知道2月份的死亡事件,她可能会更早发布这样的命令。

“我认为,如果我们能够更早地进行广泛检测,如果我们能够追踪记录县内的传播水平,如果我们当时就知道已经有人死亡,我们可能会比现在更早采取行动,”科迪说。她说,官员们听说很多人都生病了,但他们没有达到检测标准。

“只是因为我们认为疾控中心的检测能力非常非常非常有限,”她说。如果有可疑病例,医生会打电话给他们,县卫生当局会解释说,这些病例不符合检测条件。

“越来越让人不安,对不对?”她说。“这完全说不通。如果你只检测有旅行记录的人,那要怎么检测出社区传播?于是,就没测出来。”

 
现在还不到寻找源头的时候。越来越多证据表明,新冠病毒在美国等地实际发病时间早于2月,这没错吧,我们不谈是自然,还是人造,是哪个实验室,是投毒还是以外事故,只谈已经确定的事实。一直有人认为,如果美国不是在3月以后才开始爆发社区传染的,为什么没有发生疫情大爆发,没有发生医疗崩溃,没有封城等措施。

那么我们就看看现在已经确定的事实,2月6日加州有人死于新冠病毒,而且可以确定属于社区传播,已经存在人传人,这没错吧?

再看看美国确诊的数据:从2月6日的12到3月6日仅345,这样低的确诊数,这是确定了社区传播,人传人以后整个美国的数据,与武汉封城时的数据相比如何?是因为没有爆发,还是因为没有测试?

再看看3月6日的345发展到今天,48天,86万。

21-Jan22-Jan23-Jan24-Jan25-Jan26-Jan27-Jan28-Jan29-Jan30-Jan31-Jan1-Feb2-Feb3-Feb4-Feb5-Feb6-Feb7-Feb8-Feb9-Feb10-Feb11-Feb12-Feb13-Feb14-Feb15-Feb16-Feb17-Feb18-Feb19-Feb20-Feb21-Feb22-Feb23-Feb24-Feb25-Feb26-Feb27-Feb28-Feb29-Feb1-Mar2-Mar3-Mar4-Mar5-Mar6-Mar
USA1112255556781111111212121212131314151515151516161735353553576060667191107130162236345

6-Mar7-Mar8-Mar9-Mar10-Mar11-Mar12-Mar13-Mar14-Mar15-Mar16-Mar17-Mar18-Mar19-Mar20-Mar21-Mar22-Mar23-Mar24-Mar25-Mar26-Mar27-Mar28-Mar29-Mar30-Mar31-Mar1-Apr2-Apr3-Apr4-Apr5-Apr6-Apr7-Apr8-Apr9-Apr10-Apr11-Apr12-Apr13-Apr14-Apr15-Apr16-Apr17-Apr18-Apr19-Apr20-Apr21-Apr22-Apr
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从现在举的例子来看,只能说美国其实二月甚至一月就有人被传染,至于他们为什么没有大量传给别人,或者疫情没有飞速爆发,原因要说的话可能很多
 
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