谢谢，学习了。
不要带任何政治立场，如果可以选择的话，你选哪一款疫苗？
- 主题发起人 光放
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贵圈
政府都对党
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老向说
这是注射外源遗传物质到你的体内， 避开消化道（必须的），直接插入你的遗传信息链（插哪了？是随机插入吗？会砸断正常基因吗？），抢占遗传控制权， 产生S蛋白， 然后由S蛋白刺激人体产生抗体。而灭活疫苗是注射含S蛋白的灭活病毒直接刺激人体产生抗体。
智商高于50的人都不会选错。
光放说
选哪个疫苗跟智商有什么关系？难不成跟你的观点不同就是智商低了？
秀秀你的智商：从第一支灭活疫苗的使用，到ADE被发现用了多长时间？mRNA的历史有多久？能从理论或者逻辑上证明没有”类似“ADE的副作用因而无需担心
吗？所谓类似是广义上的各种不可预知的副作用。
看完你们两，我奋不顾身地想说一句
最好别盖牌，又不是政治话题。看看谁选了哪一个，多好？哈哈。什么咬什么？
这是注射外源遗传物质到你的体内， 避开消化道（必须的），直接插入你的遗传信息链（插哪了？是随机插入吗？会砸断正常基因吗？），抢占遗传控制权， 产生S蛋白， 然后由S蛋白刺激人体产生抗体。而灭活疫苗是注射含S蛋白的灭活病毒直接刺激人体产生抗体。
智商高于50的人都不会选错。
光放说
选哪个疫苗跟智商有什么关系？难不成跟你的观点不同就是智商低了？
秀秀你的智商：从第一支灭活疫苗的使用，到ADE被发现用了多长时间？mRNA的历史有多久？能从理论或者逻辑上证明没有”类似“ADE的副作用因而无需担心
吗？所谓类似是广义上的各种不可预知的副作用。
看完你们两，我奋不顾身地想说一句
最好别盖牌，又不是政治话题。看看谁选了哪一个，多好？哈哈。什么咬什么？
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不是很确定第3项腺病体疫苗的英文是什么？不知是不是俄国和陈薇的这类。
1. Inactivated virus
In this case, the virus is grown in large quantities in cells, and then killed, often with a chemical, which is usually formaldehyde, but heat or radiation can also be used. Two kinds of flu vaccines are made this way, grown in either chicken eggs or mammalian cells.Pros
- Unlike live virus vaccines, it can even be given to people with weakened immune systems.
Cons
- It doesn't lead to as strong an immune response as a live virus. Several doses, including boosters at regular intervals, are usually necessary.
- It requires the virus to be grown in large quantities and that can take time and may not be as easy to scale up as other kinds of vaccines.
2. RNA
With RNA vaccines, what's injected into the body is simply the genetic instructions to make a viral protein such as the spike protein. Cells in your body then use the instructions to make the protein inside the body for your immune cells to see and respond to.Pros
- No virus is needed to make the vaccine, cutting production time compared to conventional vaccines.
Cons
- Don't always produce a strong immune response compared to whole viruses, and may require adjuvants.
3. Non-replicating viral vector
Viral vectors are "carrier" viruses that don't cause the disease you're vaccinating against, such as COVID-19, but can be engineered to carry a piece of viruses such as SARS-CoV-2. Non-replicating viral vectors are viruses that have been genetically engineered so they can't replicate and cause disease. Then they're further modified to produce the protein for the disease you want, such as the coronavirus spike protein, and injected into the body to provoke an immune response.The viruses used by COVID-19 vaccine candidates include adenoviruses, MVA (modified vaccinia ankara, a weakened pox virus), parainfluenza and rabies.
Pros
- Generates more powerful immune response than subunit proteins.
- Some don't have to be stored at very low temperatures (according to China-based company CanSino), so they're viable for use in resource-limited tropical areas.
Cons
- People who have already been exposed to the viral vector, such as adenovirus, may be resistant.
- Harder to scale up than protein or DNA because a virus still needs to be grown.
- Because each virus can only infect one cell, large quantities of the virus need to be grown and injected, adding to production time.
Areacode613
新手上路
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个人简单理解：
灭活病毒 - 病毒已灭活， 有病毒的所以特征包括S蛋白，注入体内让免疫系统识别
腺病毒疫苗 - 把腺病毒整合病毒特征S蛋白，注入体内让免疫系统识别
核酸疫苗 - 把基因物质的一小段，DNA或mRNA， 注入体内， 人体自己合成病毒特征S蛋白， 然后入体的免疫系统来识别。
其中DNA疫苗有整合至人基因组引起基因突变的风险。mRNA疫苗 长期风险未知。
灭活病毒 - 病毒已灭活， 有病毒的所以特征包括S蛋白，注入体内让免疫系统识别
腺病毒疫苗 - 把腺病毒整合病毒特征S蛋白，注入体内让免疫系统识别
核酸疫苗 - 把基因物质的一小段，DNA或mRNA， 注入体内， 人体自己合成病毒特征S蛋白， 然后入体的免疫系统来识别。
其中DNA疫苗有整合至人基因组引起基因突变的风险。mRNA疫苗 长期风险未知。
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我的理解这就是光放说的mRNA 疫苗的历史太短，属于首次研发，使用，因此 长期风险未知。
InterMilan7
资深人士
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。不过这上面的投票也只是个大概意向。
