除了不明原因的超额死亡, 阿片类药物滥用已经是美国第一致死原因, 但是, CDC应声放款阿片类处方药

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美国最高公共卫生机构周四放宽了对美国医生开具羟考酮(oxycodone)以及其他阿片类止痛药的指导意见。

据报道,这是美国疾病控制和预防中心(CDC)在2016年后首度更新相关指南,这一指南推动了阿片类处方的减少。

报道指出,阿片类止痛药可能会让人上瘾,即使是在医生的指导下使用。它也被确认为二十多年前开始的美国药物过量事件上升的一个重要原因,尽管主要是由于非法药物而非处方药。不过,据报道目前其他药物在用药过量的统计数据中已经超过了阿片类,非法芬太尼现在是导致死亡的最大原因。

有部分专家表示,以前的指南成功地减少了不适当和危险的处方,但是它也成为了医疗护理的障碍,一些药剂师拒绝按照医生开的处方开药。

CDC表示,这一改变旨在确保病人得到富有同情心和安全的疼痛护理。


据报道,周四发布的新指南包括12条建议,供临床医生针对成年人,为持续时间不到一个月的急性疼痛、持续时间一到三个月的亚急性疼痛和持续时间超过三个月的慢性疼痛开具阿片类药物处方。

报道称,更新内容包括更多地关注治疗短期急性和亚急性疼痛,以及更多地强调临床医生和已经接受阿片类药物治疗的患者合作评估长期使用阿片类药物的风险和好处。

据报道,一些主要的变化如下:

CDC不再建议将急性疼痛的阿片类药物治疗限制在三天之内;

该机构放弃了建议医生避免将吗啡剂量增加到相当于每天90毫克水平的具体建议; 对于接受较高剂量阿片类药物治疗的患者,CDC敦促医生不要突然停止治疗,除非有迹象表明存在威胁生命的危险。该机构提出了如何让患者逐渐停药的建议。
 

Fact-check: Is fentanyl the leading cause of death among American adults?​

Nusaiba Mizan
Austin American-Statesman

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The U.S. reached a grim milestone in April 2021: more than 100,000 Americans died of drug overdoses in a single year. The U.S. Centers for Disease Control and Prevention press release on this statistic indicated that opioids, especially the synthetic opioid fentanyl, drove the rise.
U.S. Rep. Beth Van Duyne, R-Irving, tweeted on Aug. 19: "Fentanyl is the leading cause of death among American adults.”

The nation is grappling with a surge in deaths from opioids. And there’s no question fentanyl is a key factor driving up those fatalities. Fentanyl is similar to morphine but is 50 to 100 times more potent, according to the National Institute on Drug Abuse.We reached out to Van Duyne's office to ask for her source for the statement but didn’t hear back. Van Duyne’s office however did provide the Associated Press, undertaking a similar fact check, an analysis by Families Against Fentanyl, which specified an age range in its analysis.
The advocacy group Families Against Fentanyl examined CDC data and determined fentanyl has become the leading cause of death for people ages 18 to 45 in 2019 and 2020. The group compared synthetic-opioid related deaths with other major causes of death, which were listed in another CDC data set on leading causes of death.
Here’s what we know:
The CDC collects data revealing the leading causes of death in the U.S. In 2020, the leading causes of death among all American adults were heart disease, cancer, and COVID-19. Provisional data for 2021 indicates these same health issues have continued to be the leading causes of death.
"Far more people die from cancer, heart disease and COVID-19, compared to fentanyl overdose,” said Scott Walters, a professor of behavioral health at the University of North Texas Health Science Center at Fort Worth. Walters has been instrumental in work designed to address the opioid crisis in hard-hit communities in several states.
In 2020, more than 56,000 people ages 18 and older died in synthetic opioid-related incidents, according to data made available through the CDC’s online mortality database. In 2021, nearly 70,000 people 18 and older died in synthetic opioid-related incidents.
On whether fentanyl overdose is the leading cause of death for the 18-45 age range, a CDC spokesperson neither affirmed nor denied the statistic.
Fentanyl-related deaths are coded as synthetic opioid-related deaths. Fentanyl comprises approximately 90% of the synthetic opioids category, the CDC said.
The spokesperson said “accidents (unintentional injuries)” was the leading cause of death in the age 18-45 group in 2021.
If one were to break out the unintentional injury category to make the drug categories rankable, the leading cause for people ages 18-45 would be unintentional drug overdose due to synthetic opioids. That number would exceed the second highest leading cause of death (suicide in 2020 and COVID-19 in 2021.)
In an email to PolitiFact Texas, the CDC spokesperson said, “If one assumes that the other synthetic narcotics category for those 18-45 is 90% fentanyl, then one can argue that unintentional fentanyl overdose is likely the leading cause in that age group. However, because we don’t have exact numbers of fentanyl deaths for that age category, we cannot say for certain that this is accurate.”
The spokesperson also noted overdose deaths are spread out across four different death categories: accidents, suicide, homicide, and undetermined.
Public health advocates are sounding the alarm about opioids with good reason.
Scott Walters and researcher Joseph Friedman at UCLA David Geffen School of Medicine told PolitiFact Texas synthetic opioid-related deaths is — or is likely — the leading cause of death for adults age 18 to 45.
Brown University professor of epidemiology Brandon Marshall said drug overdose, as a broader category, is the leading cause of death among adults ages 18 to 45 with fentanyl playing a contributing role in most of them. Marshall cautioned, however, that many of these deaths are attributed to multiple substances, not solely fentanyl.There are many ways to slice the data in the CDC database, according to experts. Depending on which underlying causes of death are chosen in the database alongside the synthetic opioid cause-of-death code, the data can yield different numbers for the number of synthetic opioid-related deaths.
Michigan State University researcher Matthew Myers said synthetic opioids are the leading cause of death among adults ages 18-45. Data he pulled indicated there are a higher number of synthetic opioid deaths other than methadone compared to firearm deaths, cardiovascular disease, motor vehicle accidents, and cancer.
Dr. Lewis Nelson, chief of the Division of Medical Toxicology at Rutgers New Jersey Medical School and University Hospital, said it is plausible to say fentanyl overdoses are the leading cause of death for that age range, depending on how thinly you slice the information and data.
If you look at the data, you don’t see any cause of death category that comes near that level of synthetic opioid-related deaths, Nelson said.
You also could argue that this data, reported from death certificates, are an underestimate, Nelson said. Many jurisdictions across the country, staffed by coroners or medical examiners without a lot of funds, might not drug test people who die.
“They might just put multi-drug intoxication or something else, and that would not be counted as a fentanyl death,” Nelson said.
On the other hand, Nelson said, if fentanyl is found in the body after death, then the death would be coded with synthetic opioids even if it is not the lethal agent. For example, if someone dies of a gunshot wound but also had fentanyl in their body, the synthetic opioids would be coded as an associated factor for the death.

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民主社会,政客的第一要务是讨好选民而不是造福于民。
 
逻辑上, 某个东西成为第一死因, 我怎么赶脚,咱应该更加谨慎地控制呢. 何况这个东西上瘾.
 
民主社会,政客的第一要务是讨好选民而不是造福于民。
讨好选民, 就是杀死他们吗?

这不是竭泽而渔?
 
公卫机构, 司机们, 到底要干什么?
 
增加其他的死亡因素为了掩盖超额死亡的真正原因?
 
激进自由主义倾向于相信事物的表面。而不去深究。

造成的结果包括乌托邦,包括mrna。


芬太尼等啊片物质,在美国正规药店已经滥用。现在更加放松管理。只会造成更多的成瘾。更多的死亡。
 
大麻合法化除了收税,没有其它的益处。但是害处是长远的。
 
激进自由主义倾向于相信事物的表面。而不去深究。

造成的结果包括乌托邦,包括mrna。


芬太尼等啊片物质,在美国正规药店已经滥用。现在更加放松管理。只会造成更多的成瘾。更多的死亡。

有一腚道理。

要以___主义指导科研。请填空。
 
科学的数据已经证实啊片在美国药店已经泛滥了。
 
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