用羟氯喹治愈699例 纽约一医生成功率100%
- 主题发起人 葡萄干
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钟南山在2月，对此药的评价是非特效药，而是有效药，但是很遗憾，有不同的声音：
在中国的一个30例的试验中羟氯喹并没有比安慰剂更有效，需要更大规模的试验。
Covid Report: A Trump-Touted Malaria Drug Flops In Coronavirus Treatment
- ALLISON GATLIN
- 04:22 PM ET 03/24/2020
The study, performed in China, followed 30 patients with mild symptoms. It investigated hydroxychloroquine, a cousin of chloroquine. Both can treat malaria, lupus and rheumatoid arthritis. In recent days, Trump has reiterated his positive views on their potential in coronavirus treatment.
But the drug didn't pan out in the study, Evercore ISI analyst Umer Raffat said in a note to clients. He described the results as "far from positive." Of three key measures, just one favored the use of the malaria drugs in coronavirus treatment.
"It really puzzles me why we're seeing inaccurate characterizations of clinical data," Raffat said. "In my honest opinion, having an honest discussion around emerging clinical data would actually help the progress."
https://shop.investors.com/Products...rgt|PRSNL|2020|03|ibdd|na||573935&src=A00492A
Malaria Drugs In Coronavirus Treatment?
Still, generic pharmaceutical companies Teva Pharmaceutical (TEVA) and Mylan (MYL), which are increasing production of hydroxychloroquine tablets for potential coronavirus treatment, notched gains Tuesday.
On the stock market today, Teva stock jumped 8.4%, to 8.12. Shares of Mylan reversed an earlier rise and declined 3.8%, to 15.14, at the closing bell. Pharma giants Novartis (NVS), Sanofi (SNY) and Bayer (BAYRY) also pledged to ramp production of the malaria drugs. Shares of all three also popped.
Researchers saw the potential for chloroquine in coronavirus treatment in February, SVB Leerink analyst Ami Fadia said in his report to clients.
Hydroxychloroquine is a related drug with less severe side effects, allowing for higher doses and fewer interactions with other drugs.
This could be key in coronavirus treatment. To date, the new form of coronavirus, dubbed Covid-19, has infected more than 416,000 people worldwide. That includes nearly 19,000 deaths. More than 108,000 people have recovered, according to Worldometers.
Covid-19 Study Doesn't Bode Well
The hydroxychloroquine study examined virological clearance — the medicine's ability to lower how much of the virus remains in the body. After a week, the placebo cleared 93% of the virus vs. 87% clearance for those who received hydroxychloroquine, Raffat said.
Further, patients' temperatures normalized on the same day for both groups.
Only radiological progression measured by CT scan favored hydroxychloroquine in coronavirus treatment. But the data are hard to interpret due to the small number of patients, Raffat said. He questioned the dosage and patients' baseline viral loads. That information wasn't disclosed.
"Parsing through the emerging data for these important drives of success can help define what an effective treatment window and optimal candidate looks like," he said.
Pharma Companies Ramp Production
Regardless, Trump's endorsement has spurred pharma companies to ramp production of these old malaria drugs to use in coronavirus treatment. The market for hydroxychloroquine pills is worth around $450 million, SVB Leerink's Fadia said.
Fadia doesn't expect hydroxychloroquine in coronavirus treatment to be a huge moneymaker for generic pharmaceutical companies.
"But the efforts by these companies to step in to help combat the Covid-19 pandemic would be a good reminder for various constituents of the important role generic companies play in the health care system," she said.
Prescriptions are increasing and were 20% above normal for the week ending March 13, she said. The Lupus Foundation of America urged drug manufacturers on Monday to ensure they produce enough chloroquine and hydroxychloroquine to continue reaching lupus patients.
"Unfortunately, there are already verified reports across the country of pharmacies having major shortages of these vital drugs," the foundation said in a written statement. This is problematic for some lupus patients who don't have alternative medications.
Banner Health, a hospital system in Arizona, also cautioned against self-medicating for coronavirus treatment. A man died and his wife is in critical condition after the couple ingested chloroquine phosphate. This compound is commonly used at aquariums to clean fish tanks.
Covid Report: A Trump-Touted Malaria Drug Flops In Coronavirus Treatment
A decades old malaria drug touted by President Donald Trump as a potential coronavirus treatment failed to impress in an early-stage study.
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真希望是特效药，再观察一段，看看美国治愈率有没有显著的提升吧。钟南山在2月，对此药的评价是非特效药，而是有效药，但是很遗憾，有不同的声音：
在中国的一个30例的试验中羟氯喹并没有比安慰剂更有效，需要更大规模的试验。
Covid Report: A Trump-Touted Malaria Drug Flops In Coronavirus Treatment
A decades-old malaria drug touted by President Donald Trump as a potential coronavirus treatment has failed to impress in an early-stage study.
- ALLISON GATLIN
- 04:22 PM ET 03/24/2020
The study, performed in China, followed 30 patients with mild symptoms. It investigated hydroxychloroquine, a cousin of chloroquine. Both can treat malaria, lupus and rheumatoid arthritis. In recent days, Trump has reiterated his positive views on their potential in coronavirus treatment.
But the drug didn't pan out in the study, Evercore ISI analyst Umer Raffat said in a note to clients. He described the results as "far from positive." Of three key measures, just one favored the use of the malaria drugs in coronavirus treatment.
"It really puzzles me why we're seeing inaccurate characterizations of clinical data," Raffat said. "In my honest opinion, having an honest discussion around emerging clinical data would actually help the progress."
https://shop.investors.com/Products...rgt|PRSNL|2020|03|ibdd|na||573935&src=A00492A
Malaria Drugs In Coronavirus Treatment?
Still, generic pharmaceutical companies Teva Pharmaceutical (TEVA) and Mylan (MYL), which are increasing production of hydroxychloroquine tablets for potential coronavirus treatment, notched gains Tuesday.
On the stock market today, Teva stock jumped 8.4%, to 8.12. Shares of Mylan reversed an earlier rise and declined 3.8%, to 15.14, at the closing bell. Pharma giants Novartis (NVS), Sanofi (SNY) and Bayer (BAYRY) also pledged to ramp production of the malaria drugs. Shares of all three also popped.
Researchers saw the potential for chloroquine in coronavirus treatment in February, SVB Leerink analyst Ami Fadia said in his report to clients.
Hydroxychloroquine is a related drug with less severe side effects, allowing for higher doses and fewer interactions with other drugs.
This could be key in coronavirus treatment. To date, the new form of coronavirus, dubbed Covid-19, has infected more than 416,000 people worldwide. That includes nearly 19,000 deaths. More than 108,000 people have recovered, according to Worldometers.
Covid-19 Study Doesn't Bode Well
The hydroxychloroquine study examined virological clearance — the medicine's ability to lower how much of the virus remains in the body. After a week, the placebo cleared 93% of the virus vs. 87% clearance for those who received hydroxychloroquine, Raffat said.
Further, patients' temperatures normalized on the same day for both groups.
Only radiological progression measured by CT scan favored hydroxychloroquine in coronavirus treatment. But the data are hard to interpret due to the small number of patients, Raffat said. He questioned the dosage and patients' baseline viral loads. That information wasn't disclosed.
"Parsing through the emerging data for these important drives of success can help define what an effective treatment window and optimal candidate looks like," he said.
Pharma Companies Ramp Production
Regardless, Trump's endorsement has spurred pharma companies to ramp production of these old malaria drugs to use in coronavirus treatment. The market for hydroxychloroquine pills is worth around $450 million, SVB Leerink's Fadia said.
Fadia doesn't expect hydroxychloroquine in coronavirus treatment to be a huge moneymaker for generic pharmaceutical companies.
"But the efforts by these companies to step in to help combat the Covid-19 pandemic would be a good reminder for various constituents of the important role generic companies play in the health care system," she said.
Prescriptions are increasing and were 20% above normal for the week ending March 13, she said. The Lupus Foundation of America urged drug manufacturers on Monday to ensure they produce enough chloroquine and hydroxychloroquine to continue reaching lupus patients.
"Unfortunately, there are already verified reports across the country of pharmacies having major shortages of these vital drugs," the foundation said in a written statement. This is problematic for some lupus patients who don't have alternative medications.
Banner Health, a hospital system in Arizona, also cautioned against self-medicating for coronavirus treatment. A man died and his wife is in critical condition after the couple ingested chloroquine phosphate. This compound is commonly used at aquariums to clean fish tanks.
Covid Report: A Trump-Touted Malaria Drug Flops In Coronavirus Treatment
A decades old malaria drug touted by President Donald Trump as a potential coronavirus treatment failed to impress in an early-stage study.
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在世界很多国家都证明硫酸羟氯喹有用的时候，只有中国政府和它的御用专家逆天说没有用。钟南山在2月，对此药的评价是非特效药，而是有效药，但是很遗憾，有不同的声音：
在中国的一个30例的试验中羟氯喹并没有比安慰剂更有效，需要更大规模的试验。
Covid Report: A Trump-Touted Malaria Drug Flops In Coronavirus Treatment
A decades-old malaria drug touted by President Donald Trump as a potential coronavirus treatment has failed to impress in an early-stage study.
- ALLISON GATLIN
- 04:22 PM ET 03/24/2020
The study, performed in China, followed 30 patients with mild symptoms. It investigated hydroxychloroquine, a cousin of chloroquine. Both can treat malaria, lupus and rheumatoid arthritis. In recent days, Trump has reiterated his positive views on their potential in coronavirus treatment.
But the drug didn't pan out in the study, Evercore ISI analyst Umer Raffat said in a note to clients. He described the results as "far from positive." Of three key measures, just one favored the use of the malaria drugs in coronavirus treatment.
"It really puzzles me why we're seeing inaccurate characterizations of clinical data," Raffat said. "In my honest opinion, having an honest discussion around emerging clinical data would actually help the progress."
https://shop.investors.com/Products...rgt|PRSNL|2020|03|ibdd|na||573935&src=A00492A
Malaria Drugs In Coronavirus Treatment?
Still, generic pharmaceutical companies Teva Pharmaceutical (TEVA) and Mylan (MYL), which are increasing production of hydroxychloroquine tablets for potential coronavirus treatment, notched gains Tuesday.
On the stock market today, Teva stock jumped 8.4%, to 8.12. Shares of Mylan reversed an earlier rise and declined 3.8%, to 15.14, at the closing bell. Pharma giants Novartis (NVS), Sanofi (SNY) and Bayer (BAYRY) also pledged to ramp production of the malaria drugs. Shares of all three also popped.
Researchers saw the potential for chloroquine in coronavirus treatment in February, SVB Leerink analyst Ami Fadia said in his report to clients.
Hydroxychloroquine is a related drug with less severe side effects, allowing for higher doses and fewer interactions with other drugs.
This could be key in coronavirus treatment. To date, the new form of coronavirus, dubbed Covid-19, has infected more than 416,000 people worldwide. That includes nearly 19,000 deaths. More than 108,000 people have recovered, according to Worldometers.
Covid-19 Study Doesn't Bode Well
The hydroxychloroquine study examined virological clearance — the medicine's ability to lower how much of the virus remains in the body. After a week, the placebo cleared 93% of the virus vs. 87% clearance for those who received hydroxychloroquine, Raffat said.
Further, patients' temperatures normalized on the same day for both groups.
Only radiological progression measured by CT scan favored hydroxychloroquine in coronavirus treatment. But the data are hard to interpret due to the small number of patients, Raffat said. He questioned the dosage and patients' baseline viral loads. That information wasn't disclosed.
"Parsing through the emerging data for these important drives of success can help define what an effective treatment window and optimal candidate looks like," he said.
Pharma Companies Ramp Production
Regardless, Trump's endorsement has spurred pharma companies to ramp production of these old malaria drugs to use in coronavirus treatment. The market for hydroxychloroquine pills is worth around $450 million, SVB Leerink's Fadia said.
Fadia doesn't expect hydroxychloroquine in coronavirus treatment to be a huge moneymaker for generic pharmaceutical companies.
"But the efforts by these companies to step in to help combat the Covid-19 pandemic would be a good reminder for various constituents of the important role generic companies play in the health care system," she said.
Prescriptions are increasing and were 20% above normal for the week ending March 13, she said. The Lupus Foundation of America urged drug manufacturers on Monday to ensure they produce enough chloroquine and hydroxychloroquine to continue reaching lupus patients.
"Unfortunately, there are already verified reports across the country of pharmacies having major shortages of these vital drugs," the foundation said in a written statement. This is problematic for some lupus patients who don't have alternative medications.
Banner Health, a hospital system in Arizona, also cautioned against self-medicating for coronavirus treatment. A man died and his wife is in critical condition after the couple ingested chloroquine phosphate. This compound is commonly used at aquariums to clean fish tanks.
Covid Report: A Trump-Touted Malaria Drug Flops In Coronavirus Treatment
A decades old malaria drug touted by President Donald Trump as a potential coronavirus treatment failed to impress in an early-stage study.
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据我看到的报道，说此药没用的是：
https://www.investors.com/news/tech...t-trump-touted-malaria-drug-fails-to-impress/
钟南山从一个多月以前，就多次说氯喹是治疗此病的有效药，而且安全性高。还要贴几遍？
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没有研究对比过，也没有见过这些数据。
Littlecesar
本站元老
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如果消息和669例数据属实的话，那真是一大喜讯。
By the way, “羟氯喹”我有两个字不会读唉，大家都会吗？还是我理科生中文太差？
By the way, “羟氯喹”我有两个字不会读唉，大家都会吗？还是我理科生中文太差？
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qiang 基，就是 OH,氯喹，是带有氯Cl 的喹（kui)宁，治疟疾的，金鸡纳霜。
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是的，我也是这样想，正反两方面的信息都收集，这药便宜，如果见效，是福音。
